Four Pharmacological Categories of Pain

In order to provide adequate pain control we must first diagnosis the cause of each type of pain so we can use effective medications.  From a pharmacological point of view chronic pain can be divided into four overall categories:
  1. Opioid responsive pain - pain that responds well to increasingly large dose of opioid analgesics, such as codeine or morphine.  An example is soft tissue pain.
  2. Opioid non-responsive pain - Pain that does not respond to opioid analgesia regardless how severe it may be.  Other drugs must be used.  A good example is differentiation, or nerve pain, caused by nerve destruction.  The burning pain associated with nerve pain is relived by an anticonvulsant.  muscle pain is relieved by some tranquilizers or injections of a local anesthetic and a corticosteriod.
  3. Pain that is partially responsive to opioids - Pain such as bone pain is only partially responsive to opioids and requires the use of adjuvant drugs.
  4. Pain that is opioid responsive but the use of opioids is inappropriate - pain such as bowel pain, including constipation or irritable bowl syndrome, is a good example.  "Squashed stomach" is another example.

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